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AB Nexus announces new grant awards with a focus on research collaborations related to AI and climate change

Anonymous — Tue, 23 Jul 2024 14:14:45 +0000

AB Nexus announces new grant awards with a focus on research collaborations related to AI and climate change Anonymous (not verified) Tue, 07/23/2024 - 08:14

Megan Lane

Today, the AB Nexus program announced its 2024 seed grant awards to interdisciplinary research teams from the University of Colorado Anschutz Medical Campus and the University of Colorado Boulder. Collectively, the seven winning teams will receive $713,000 in funding to advance cutting-edge research that improves human health and well-being.

AB Nexus is a unique program that provides joint-campus funding and resources to catalyze research collaborations between CU Boulder and CU Anschutz. By fostering intercampus partnerships between scientists, engineers and physicians from diverse disciplines, AB Nexus has helped to advance new innovations and discoveries while growing CU’s collective research enterprise.

”AB Nexus has created a new culture of research collaboration at the University of Colorado,” said Thomas Flaig, MD, vice chancellor for research at CU Anschutz. “Solving the toughest challenges in human health requires teamwork across a wide range of fields, and we’re very proud of how this program has helped to inspire so many new interdisciplinary research projects across our campuses.”

Accelerating collaborative research in human health and wellness

I'm thrilled to receive an AB Nexus seed grant for my collaboration with Dr. Ben Bitler at CU Anschutz. The research this award supports will transform our ability to leverage advanced data to identify new targets for treating patients with ovarian cancer."

—Professor Aaron Clauset, Department of Computer Science; BioFrontiers Institute (CU Boulder)

Since launching in 2020, AB Nexus has awarded more than $4.2 million in seed funding to 55 collaborative research teams, several of which have gone on to secure additional external funding and publish peer-reviewed research papers that are helping to improve health care and medicine.

For example, one team that received a $125,000 AB Nexus seed grant in 2020 was recently awarded up to $39 million in funding from the federal government’s Advanced Research Projects Agency for Health (ARPA-H). The team of scientists from CU Boulder, CU Anschutz and Colorado State University is working to develop new regenerative treatments for osteoarthritis.

“Within five years, our goal is to develop a suite of non-invasive therapies that can end osteoarthritis,” said project leader and Principal Investigator Stephanie Bryant, professor in the Department of Chemical and Biological Engineering, Materials Science and Engineering at CU Boulder. “It could be an absolute game-changer for patients.”

Awarded teams to tackle wide range of health challenges

The 2024 AB Nexus awardees include three newly formed teams and four projects that expand upon existing collaborations. Individual grants range in size from $65,000 to $125,000, and this year’s funds include generous co-sponsor support: $100,000 from the University of Colorado Cancer Center and $95,000 from the Department of Computer Science at CU Boulder’s College of Engineering and Applied Science.

This year, AB Nexus developed two themed “tracks” for its grant applications. In addition to the general human health track, research teams focused on “Climate Change and Health” and “AI/Advanced Computing and Health” were invited to apply to topic-specific AB Nexus grants.

“We are identifying themes like AI and climate change to further explore research collaborations on our campuses that can significantly impact health and well-being,” said Massimo Ruzzene, vice chancellor for research and innovation and dean of the institutes at CU Boulder. “Through strategic alignment with societal needs, federal funding trends and partnership opportunities, the research projects associated with these themes are better positioned for novel discoveries and improving human health.”

Among the collaborative research projects that received AB Nexus awards in 2024:

A cardiologist and computer scientist are exploring new applications of artificial intelligence to improve medical devices like pacemakers for heart failure patients
An electrical engineer who specializes in medical imaging has teamed up with a mathematician to develop deep learning algorithms that can help doctors to better diagnose and assess accreta, a life-threatening condition involving the placenta tissue of expectant mothers
A doctor and environmental scientist are investigating how climate change could have a disproportionately negative effect on Colorado’s prison population—and how to mitigate those impacts and improve inmate health in the face of rising temperatures
An obstetrician and computer scientist are using advanced machine learning techniques to create better predictive models for the recurrence of ovarian cancer, which could lead to more personalized and effective treatments for patients

The full list of 2024 AB Nexus award winners is below. With the support of joint-campus leadership, the next AB Nexus award cycle will occur in spring 2025. More information will be available on the AB Nexus website this fall.

2024 AB Nexus Awardees

AI Optimized Pacing for Heart Failure Patients
Led by Michael Rosenberg (CU Anschutz) and Ashutosh Trivedi (CU Boulder)
Cell Cycling Adaptations in Drug-Tolerant Persister Cells in Non-Small Cell Lung Cancer
Led by Sabrina Spencer (CU Boulder) and Tejas Patil (CU Anschutz)
Cell-Type, Pathway and Neurotransmitter-Specific Regulation of Feeding Circuitry
Led by Christopher Ford, PhD (CU Anschutz) and David Root (CU Boulder)
How Tubulinopathies Disrupt Microtubules and How to Fix Them: Integration of Genetics and Computational Modeling
Led by Meredith Betterton (CU Boulder) and Jeffrey Moore (CU Anschutz)
Improved Assessment of Placenta Accreta with Fast 3D MRI,
Led by Stephen Becker (CU Boulder) and Nicholas Dwork (CU Anschutz)
Investigating Extreme Health Risks at the Nexus of Climate Change, Incarceration and Societal Re-entry in Colorado
Led by David Ciplet (CU Boulder) and Katherine LeMasters (CU Anschutz)
Using Advanced Computational Analysis to Predict Ovarian Cancer Outcomes
Led by Benjamin Bitler (CU Anschutz) and Aaron Clauset (CU Boulder)

Learn more

Today, the AB Nexus program announced its 2024 seed grant awards to interdisciplinary research teams from the University of Colorado Anschutz Medical Campus and the University of Colorado Boulder. Collectively, the seven winning teams will receive $713,000 in funding to advance cutting-edge research that improves human health and well-being.

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From crisis to action: CU’s climate health champions in focus

Anonymous — Thu, 16 May 2024 19:19:18 +0000

From crisis to action: CU’s climate health champions in focus Anonymous (not verified) Thu, 05/16/2024 - 13:19

Jay Lemery, M.D. and Katherine James, Ph.D.—based at the CU Anschutz Medical Campus—together with Jose-Luis Jimenez, Ph.D. at CU Boulder, epitomize the collaborative spirit of AB Nexus. While Lemery, James and Jimenez focus on distinct areas—such as climate medicine, water contamination and airborne transmission—all add to the collective efforts of climate adaptation and mitigation for Colorado and global communities.

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ARPA-H awards up to $39M for non-invasive osteoarthritis therapies

Anonymous — Tue, 26 Mar 2024 06:00:00 +0000

ARPA-H awards up to $39M for non-invasive osteoarthritis therapies Anonymous (not verified) Tue, 03/26/2024 - 00:00

“To truly address osteoarthritis, you have to get at both the biology and the structural problem,” said co-Principal Investigator Michael Zuscik (Department of Orthopedics, CU Anschutz). “This unique Colorado dream team we have put together has the multidisciplinary expertise, and now the resources, to tackle both at once. We can approach curing the disease like never before.”

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Joints that could heal themselves? Researchers could get there in 5 years

Anonymous — Tue, 26 Mar 2024 06:00:00 +0000

Joints that could heal themselves? Researchers could get there in 5 years Anonymous (not verified) Tue, 03/26/2024 - 00:00

The Novel Innovations for Tissue Regeneration in Osteoarthritis (NITRO) program, the first created under ARPA-H, is enabling a dream team of engineers, medical scientists and veterinarians from CU Boulder, the CU Anschutz Medical Campus and Colorado State University to make an aggressive final push toward a goal many have spent their entire careers pursuing.

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AB Nexus transforming intercampus research collaboration after just three years

Anonymous — Sun, 15 Oct 2023 06:00:00 +0000

AB Nexus transforming intercampus research collaboration after just three years Anonymous (not verified) Sun, 10/15/2023 - 00:00

The collaborative seed grant program will continue full steam ahead in Spring 2024, including the introduction of award tracks to seed research in two new, key areas of opportunity: Climate Change and Health; and Artificial Intelligence/Advanced Computing and Health.

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New AB Nexus awardees advance innovative research collaborations

Anonymous — Tue, 20 Jun 2023 06:00:00 +0000

New AB Nexus awardees advance innovative research collaborations Anonymous (not verified) Tue, 06/20/2023 - 00:00

From advancing new Alzheimer’s treatments to developing predictive computer models to help youth in crisis, newly awarded teams of researchers from the CU Anschutz Medical Campus and CU Boulder are advancing a wide range of collaborative research projects aimed at improving human health and well-being.

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Scientists pursue personalized approach to treating pelvic organ prolapse

Anonymous — Tue, 02 May 2023 06:00:00 +0000

Scientists pursue personalized approach to treating pelvic organ prolapse Anonymous (not verified) Tue, 05/02/2023 - 00:00

With vaginal birth a top cause of pelvic floor disorders, the conditions are common among women. But because the causes are multifactorial, complex and not completely understood, treatment lags. Two women scientists recently received an AB Nexus grant to help change that.

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CU research team moves one step closer to printing models of life-like 3D organs

Anonymous — Thu, 26 Jan 2023 07:00:00 +0000

CU research team moves one step closer to printing models of life-like 3D organs Anonymous (not verified) Thu, 01/26/2023 - 00:00

A team of CU researchers funded by AB Nexus has developed a new strategy for transforming medical images, such as CT or MRI scans, into incredibly detailed 3D models on the computer. The advance marks an important step toward printing lifelike representations of human anatomy that medical professionals can squish, poke and prod in the real world.

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New AB Nexus grant awards spotlight productive cross-campus collaborations

Anonymous — Wed, 16 Nov 2022 07:00:00 +0000

New AB Nexus grant awards spotlight productive cross-campus collaborations Anonymous (not verified) Wed, 11/16/2022 - 00:00

The intercampus program stimulates innovative research collaborations and progress toward solving some of our world’s most pressing health problems. After receiving funding from the AB Nexus grant program, awarded teams have attracted $13 million in outside funding and published more than 20 peer-reviewed research studies.

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Can AI detect Alzheimer’s earlier? Two researchers combine forces to find out

Anonymous — Tue, 27 Sep 2022 06:00:00 +0000

Can AI detect Alzheimer’s earlier? Two researchers combine forces to find out Anonymous (not verified) Tue, 09/27/2022 - 00:00

With funding from AB Nexus, researchers from CU Anschutz and CU Boulder are developing an artificial intelligence tool with a goal of diagnosing dementia at earlier stages, so patients and providers can plan more effective treatment options.

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